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REFLECTIONS
Dyslipidaemia
Dyslipidaemia Global Newsletter #10 2025

CONFERENCE CORNER Dyslipidaemia

The ESC Congress, hosted in Madrid, Spain on Aug 29th – Sept 1st, 2025, is the annual meeting of the
European Society of Cardiology. We present below some abstracts of interest that may have an impact
on clinical practice. Please click on the links to explore the abstracts in more detail.

STATINS AND COMBINATION THERAPY

1. Efficacy and safety of add on bempedoic acid on maximal dose of rosuvastatin and ezetimibe in patients with
established coronary artery disease (ADDBAMPIRE study). Presenter: Naveen Garg (Institute of Medical Sciences
Lucknow, India). ESC Congress 2025.
2. High- intensity lipid -lowering therapy accelerates early plaque regression: A FLOWPROMOTE sub study. Presenter:
Nadia Iraqi (Aarhus University Hospital, Denmark). ESC Congress 2025.

PCSK9 INHIBITORS

3. Effect of PCSK9 inhibitors on coronary plaque: A meta-analysis and trial sequential analysis. Presenter: Vinicus
Oliveira (Federal University of Goias, Brazil). ESC Congress 2025.

4. Oral PCSK9 inhibitors as an emerging frontier in lipid management: A meta -analysis. Presenter: Vinh Quang Tri Ho
(Debrecen, Hungary). ESC Congress 2025.

5. PCSK9 inhibitors and cardiovascular outcomes in AMI BIRISK patients: A multicenter retrospective study. Presenter:
Jiayi Ren (2nd Hospital of Tianjin Medical University, China). ESC Congress 2025.

RISK PREDICTION AND STRATIFICATION

6. Lipid management in high cardiovascular risk patients without prior myocardial infarction or stroke - preliminary
data from the VESALIUS -REAL global burden study. Presenter: Queenie Chan (Amgen Ltd, Greater London). ESC
Congress 2025.

7. Association of elevated lipoprotein(a) with future major adverse cardiovascular events in recurrent ASCVD patients:
Analysis of a large US electronic health record database. Presenter: Hannah Byrne (Dublin, Ireland). ESC Congress
2025.

8. Underestimated versus accurate assessment of cardiovascular risk in hypertensive patients: A sub- analysis of the
SNAPSHOT study in Europe. Presenter: Arman Postadzhiyan (University Hospital St. Anne, Bulgaria). ESC Congress
2025.

IMPLEMENTATION AND ADHERENCE

9. Active vs passive best -practice alerts to improve guideline -directed lipid -lowering therapy intensification in patients
with recent myocardial infarction and elevated LDL- C. Presenter: Dean Karalis (Cardiology Consultants of Philadelphia,
USA). ESC Congress 2025.
10. Statin adherence in primary care among patients with hypertension with and without other cardiometabolic
diseases. Presenter: Johan Sandslatt (University of Gothenburg, Sweden). ESC Congress 2025.

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